Platelet Rich Fibrin for Hair Loss

also known as Enriched Platelet Rich Plasma (PRP), aka. “Liquid Gold”

Platelet-rich fibrin (PRF) is the second generation of platelet-rich plasma (PRP), and the injections are used for hair growth stimulation and facial rejuvenation. As part of the body’s capacity to heal itself, platelets and other components in human blood migrate to a site of injury. Platelets are known to release a variety of factors that respond to tissue injury, where they initiate and promote healing. By concentrating platelets at the site of injury, physicians have the potential to enhance Platelet rich fibrin matrix (PRFM) is a new hair regrowth breakthrough. By tapping into your body’s own healing powers, PRFM can help restore hair growth.

  • While both PRP and PRF therapy use your body’s own platelets to stimulate healing, PRFM takes things even further.

    PRF delivers a higher concentration of growth factors. To create PRF, the blood is spun at a lower speed so that the layers of the blood do not separate out as distinctly. This allows some of the white blood cells and stem cells to remain within the platelet layer, instead of being separated. This gives PRF more healing factors than PRP. Plus, the lower centrifuge speed causes less trauma with the individual cells involved.

    PRF does not contain any additives, whereas an anticoagulant is used during the processing of the blood when making PRP. Without the anticoagulant, PRF takes the natural fibrinogen within our blood and it is converted to fibrin by thrombin in the early stages of clot formation. This creates a spongy fibrin matrix that activates the platelets that acts as a scaffolding to keep the growth factors and stem cells in the area they are injected, keeping them from diffusing, which can happen with PRP.

    PRF contains approximately 10 times the platelet concentration when compared with normal blood, as compared to 2-5x in PRP.

  • The SELPHYL® System provides the exact amount of Calcium Chloride to PRP producing Platelet-rich Fibrin Matrix.

    As soon as SELPHYL® - prepared PRFM is administered, growth factors are released through the formation of a three-dimensional cross-linked fibrin matrix which is essential to the platelet plug as it serves as a binding site for both platelets and growth factors allowing their sustained release, migration of stem cells and reservoir for regenerative signaling.

  • Step 1

    During a short office visit (20 minutes), a small amount of a patient’s own blood is drawn into a vacuum collection tube containing a cell separator gel.

    Step 2

    The tube is then placed into a centrifuge and spun for six minutes to separate the blood into a supernatant plasma/platelet suspension.

    Step 3

    The red and white blood cells are located below the cell separator gel.

    Step 4

    The platelets and plasma are then transferred in a closed system to a second vacuum tube containing a small amount of calcium chloride solution.

    Step 5

    Fibrin polymerization begins and the The PRF is extracted from the top of the vial and inserted into a syringe once the separation is complete. After that, it’s injected into your scalp and/or skin.

  • • Do Not Take ASPIRIN, IBUPROFEN (Advil, Motrin, or Nuprin), NAPROXEN (Aleve) or other Non-Steroidal Anti-Inflammatory Drugs (NSAIDS), Vitamin E, Fish Oil for 7 days before your procedure. These substances impair platelet function in the normal clotting process and thus promote bleeding and bruising.

    • Provide your body with adequate hydration for 72 hours prior to procedure. This increases the quality of your PRF for your treatment.

    • Do Not Drink Alcohol for 1 day prior to Procedure, this may cause excessive bleeding, decreased resistance to

    • EAT: You should have a meal before arriving at the office and avoid caffeine the morning of your procedure.

  • You may take ACETAMINOPHEN (TYLENOL) over-the-counter if you feel any soreness.

    Avoid washing your hair the day of the procedure.

    DO NOT apply ice packs on your scalp after the procedure, as the cold can inhibit the PRF activity.

    Your scalp may have localized swelling and/or redness at the injection sites for several hours after your procedure.

    You may resume heat and/or chemical styling (such as blow drying, coloring, curling) 2 days after your procedure.